Recent quantitative genetic research on psychotic experiences: new approaches to old questions
نویسنده
چکیده
It is common, particularly in young people, to report psychotic experiences (PEs) such as feeling paranoid and having hallucinations. The questions of the role of genes and environment on PEs in the general population, and how PEs relate to schizophrenia, have not, until recently, been addressed empirically. New approaches demonstrate the heritability and role of the environment on the full range of PEs (including positive, cognitive and negative types) and show that extreme, severe forms are linked genetically to milder, less severe forms. New approaches have tested whether PEs are associated with the genome-wide significant genetic variants known to predict schizophrenia. Although at an early stage, this research will impact how we understand PEs in everyday life.
منابع مشابه
Characterization of Psychotic Experiences in Adolescence Using the Specific Psychotic Experiences Questionnaire: Findings From a Study of 5000 16-Year-Old Twins
We aimed to characterize multiple psychotic experiences, each assessed on a spectrum of severity (ie, quantitatively), in a general population sample of adolescents. Over five thousand 16-year-old twins and their parents completed the newly devised Specific Psychotic Experiences Questionnaire (SPEQ); a subsample repeated it approximately 9 months later. SPEQ was investigated in terms of factor ...
متن کاملComparing Experiential Approaches: Structured Language Learning Experiences versus Conversation Partners for Changing Pre-Service Teacher Beliefs
Research has shown that language teachers’ beliefs are often difficult to change through education. Experiential learning may help, but more research is needed to understand how experiential approaches shape perceptions. This study compares two approaches, conversation partners (CONV) and structured language learning experiences (SLLE), integrated into a course in language acquisition. Partici...
متن کاملConsistent etiology of severe, frequent psychotic experiences and milder, less frequent manifestations: a twin study of specific psychotic experiences in adolescence.
IMPORTANCE The onset of psychosis is usually preceded by psychotic experiences (PE). Little is known about the etiology of PE and whether the degree of genetic and environmental influences varies across different levels of severity. A recognized challenge is to identify individuals at high risk of developing psychotic disorders prior to disease onset. OBJECTIVES To investigate the degree of g...
متن کاملThe structure of psychopathology: toward an expanded quantitative empirical model.
There has been substantial recent interest in the development of a quantitative, empirically based model of psychopathology. However, the majority of pertinent research has focused on analyses of diagnoses, as described in current official nosologies. This is a significant limitation because existing diagnostic categories are often heterogeneous. In the current research, we aimed to redress thi...
متن کاملAssociation between stressful life events and psychotic experiences in adolescence: evidence for gene–environment correlations
BACKGROUND Stressful life events (SLEs) are associated with psychotic experiences. SLEs might act as an environmental risk factor, but may also share a genetic propensity with psychotic experiences. AIMS To estimate the extent to which genetic and environmental factors influence the relationship between SLEs and psychotic experiences. METHOD Self- and parent reports from a community-based t...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Current Opinion in Behavioral Sciences
دوره 2 شماره
صفحات -
تاریخ انتشار 2015